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Andriol (Testosterone undecanoate) Profile

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Steroid Profile : Andriol (Testosterone undecanoate)

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Andriol is a fairly recently developed steroid. A new attempt at making an orally available testosterone. The delivery system used for andriol is quite novel in itself and shows a lot of promise. If it weren't for a few quirks this delivery method could have caught on fast.

The demand for an oral steroid that can be used for lengthy treatment has been high since the very beginning. First of all its never easy for a doctor to sell his patients on injection protocols (many fear or at least dislike needles) and for the doctor too it would be easier if the patient could take a pill than to have him come back every other week for an injection. So the pressure was on to create a steroid that wouldn't require a 17-alpha-methyl alteration.

The answer was to seek a new way of delivery, that bypassed the liver, so that no alteration was needed to protect the steroid from being deactivated in the liver. That way was found in lymphatic absorption.

With Andriol the steroid is dissolved in a type of sterile oil and then sealed inside a capsule. As a whole, the dissolved steroid is then easily absorbed by the lymphatic system, prior to passing the liver, and delivered with ease to the heart where it is then sent out across the body. The system itself is ingenious and in theory perfect. Maximal delivery and no hepatoxicity. A potent steroid capable of being used for long treatments. However in practice things don't always turn out the way they appear in theory. In studies done on both men and women, andriol was shown to be a mild and inconsistent steroid. Mild is a problem that is easily solved with higher doses, but inconsistency was the biggest problem. It seems that the amount that was delivered and the peak levels of testosterone in the blood as well as the length of activity differed not only from person to person, but from day to day. That means a different person, from day to day, will get very varying levels of testosterone in the blood. And the differences were not minor.

One subject may have a peak level of 5 ng/mmol while another can have in excess of 50 ng/mmol. What's worse, the same person may get these levels on different days. In terms of its anabolic use, that means doses of 8-16 caps per day are being used. That's more than most will inject per week of the shorter cypionate esters. Normally 1 cap delivers 40 mg of testosterone undecanoate. An ester releases the steroid in the blood, leaving us with approximately 25 mg of testosterone per cap (it's a long and heavy ester). That's 200-400 mg per day being used.

As far as the properties of this steroid go, like a propionate ester or a suspension injection, levels of testosterone, DHT and estrogen are easy to control, which makes this steroid a possibility for use during any time of the year, whether the athlete be cutting or bulking. The water retention is less notable than with longer esters, and if too high is easily controlled with Proviron or Nolvadex. Its pure testosterone, so if delivered in high enough doses, for reasons previously stated, it is of course a good mass builder with all the characteristics of testosterone. No more no less. It is of course a safe (to the liver), controllable oral steroid that can be used for extended periods of time, which does spark the interest of some, but anybody serious about gains will usually find andriol a very poor buy.Great invention for the medical world, but of little to no interest to the serious athlete.

Andriol doesn't have that many uses. When utilized in doses of 8-16 caps per day are used and it can obviously be stacked with most other steroids. Water retention problems that are common with testosterone are usually controllable enough to warrant use even during cutting phases, if not Proviron can be added to maximize its potential. The use of ancillaries is generally not required as its very mild to begin with and most problems can be solved by discontinuing use or lowering the dose. The usual anti-estrogens can still be used.

Capsules are best spread out throughout the day. Most oral steroids have a 17-alpha-methyl alteration that changes affinity and binding of the steroid, so that a single dose is usually enough. With andriol delivery is swift, peak doses high, but the steroid never outlasts its half-life of 3-5 hours. So it should be taken in three equal doses throughout the day, preferably with meals as lymphatic absorption is promoted in the presence of bile and other secretions in the GI tract.


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